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Linerase: Skin Regeneration



Linerase is a medical device class III, it is heterologous type I collagen powder which stimulates the production of new fibroblasts that create native type III collagen, a process that is the cornerstone of cosmetic medicine and anti-aging treatments. This product has already been used for almost 30 years in the form of a lyophilized collagen patch and it is still used today with success for the following treatments: healing of skin ulcers, open wounds, scars and bedsores. Linerase is safe, without side effects and does not induce any allergic reactions, while also giving excellent results.

Powder of equine collagen Type I

Each package of LINERASE consists of a glass bottle containing 100 mg of powder of equine type I collagen, sterile and pyrogen-free.


LINERASE produces the optimal conditions for the restoration of the connective tissue. It’s indicated as an adjunct in dermal bio-revitalization and to help the regeneration of the connective tissue of the dermis creating the optimal conditions for the physiological neo-formation of collagen. It is used for body and facial chrono and photo-aging.

LINERASE must be brought in suspension immediately before use, in WFI (Water For Injection) in the ratio of 100 mg collagen / 5,0 ml WFI. Once in suspension, the product must be used immediately and any residue should be discarded. The device is single-use disposable. The product is administered through intradermal infiltration using the appropriate size needles from 30G 4mm up to 30G 12 mm. To ensure a perfect sealing and prevent leakage during administration, make sure that the needle is securely fastened to the syringe. The intradermal infiltration can only be performed by physicians. LINERASE is indicated for the stimulation of fibroblasts to produce neo endogenous collagen as a new tissue filling.


This device must be injected into the dermis or the mucous membrane of the lips by a licensed physician in accordance with local laws. The technical skill of the doctor is essential for the success of the treatment. The device should be used by physicians who have received a specific training on the mesotherapic injection technique. After the injection, it is important to massage the area treated to ensure a uniform distribution of the product.

Use normal precautions for intradermal infiltrations.
The product is hypoallergenic. There are no reported side effects.

Each pack contains 1 glass vial of 100 mg of collagen powder and instructions for use.